Melanocortin Receptor 1 (MC1R) Mutations and Coat Color in Pigs

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Melanocortin receptor 1 (MC1R) mutations and coat color in pigs.

The melanocortin receptor 1 (MC1R) plays a central role in regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis within the mammalian melanocyte and is encoded by the classical Extension (E) coat color locus. Sequence analysis of MC1R from seven porcine breeds revealed a total of four allelic variants corresponding to five different E alleles. The European wild boar poss...

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Genetics of Coat Color I: The Melanocortin 1 Receptor (MC1R)

ISSN: 1937-9056 Copyright © 2008 Answers in Genesis. All rights reserved. Consent is given to unlimited copying, downloading, quoting from, and distribution of this article for non-commercial, non-sale purposes only, provided the following conditions are met: the author of the article is clearly identified; Answers in Genesis is acknowledged as the copyright owner; Answers Research Journal and ...

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Polymorphisms in Melanocortin Receptor 1 Gene in Goat Breeds: A Window for Coat Color Controling Mechanism

The broad goal of this research was to examine the nature of the Melanocortin receptor 1 (MC1R) locus on the coat color phenotype of seven goat breeds with different color coat. Blood samples were collected from five Iranian indigenous (Khalkhal, Markhor, Naeini, Najdi and Tali) and two exotic (Cashmere and Saanen) goat breeds. Polymerase chain reaction restriction fragment length polymorphism ...

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polymorphisms in melanocortin receptor 1 gene in goat breeds: a window for coat color controling mechanism

the broad goal of this research was to examine the nature of the melanocortin receptor 1 (mc1r) locus on the coat color phenotype of seven goat breeds with different color coat. blood samples were collected from five iranian indigenous (khalkhal, markhor, naeini, najdi and tali) and two exotic (cashmere and saanen) goat breeds. polymerase chain reaction restriction fragment length polymorphism ...

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Coat colours in the Massese sheep breed are associated with mutations in the agouti signalling protein (ASIP) and melanocortin 1 receptor (MC1R) genes.

Massese is an Italian dairy sheep breed characterized by animals with black skin and horns and black or apparent grey hairs. Owing to the presence of these two coat colour types, this breed can be considered an interesting model to evaluate the effects of coat colour gene polymorphisms on this phenotypic trait. Two main loci have been already shown to affect coat colour in sheep: Agouti and Ext...

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ژورنال

عنوان ژورنال: Genetics

سال: 1998

ISSN: 1943-2631

DOI: 10.1093/genetics/150.3.1177